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Ourse for HMVEC. HMVEC were treated with IgG antibody to 10 mg/ml HLA or control IgG or thrombin for 0 ? h (n 3 SD; P 0.05 for control IgG vs. antibody to HLA for 30 ?60 min).Fig. 2. C5a activates endothelial exocytosis. (A) Dose esponse. HAEC were treated with C5a or thrombin for 1 h. The release of VWF was measured as above (n 3 SD; *, P 0.05 vs. 0 ng/ml). (B) Time course. HAEC were treated with
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